League Table
| Team | Form | P | W | D | L | GF | GA | GD | PTS | | 1 | Bayer 04 Leverkusen | D W W W L | 42 | 23 | 14 | 5 | 75 | 40 | 35 | 83 |
| 2 | Napoli | W W W L W | 42 | 22 | 12 | 8 | 73 | 43 | 30 | 78 |
| 3 | Inter | D W L W D | 42 | 19 | 12 | 11 | 54 | 42 | 12 | 69 |
| 4 | Roma | W W L W L | 42 | 20 | 8 | 14 | 66 | 46 | 20 | 68 |
| 5 | Chelsea | W L W L L | 42 | 19 | 10 | 13 | 67 | 50 | 17 | 67 |
| 6 | Milan | W D W W L | 42 | 20 | 5 | 17 | 66 | 63 | 3 | 65 |
| 7 | Borussia Dortmund | D L D L L | 42 | 16 | 15 | 11 | 61 | 47 | 14 | 63 |
| 8 | RB Leipzig | L L W W W | 42 | 17 | 12 | 13 | 50 | 54 | -4 | 63 |
| 9 | Sevilla FC | L L D W W | 42 | 18 | 8 | 16 | 57 | 54 | 3 | 62 |
| 10 | Villarreal CF | W L W L D | 42 | 16 | 11 | 15 | 58 | 61 | -3 | 59 |
| 11 | Newcastle United | W W L W W | 42 | 15 | 12 | 15 | 56 | 55 | 1 | 57 |
| 12 | Tottenham Hotspur | L W L W W | 42 | 15 | 10 | 17 | 63 | 63 | 0 | 55 |
| 13 | Juventus | L L L D W | 42 | 16 | 7 | 19 | 62 | 62 | 0 | 55 |
| 14 | Aston Villa | L D D L D | 42 | 13 | 16 | 13 | 57 | 58 | -1 | 55 |
| 15 | Al Nassr | W W L L L | 42 | 16 | 5 | 21 | 57 | 58 | -1 | 53 |
| 16 | Lazio | D D W W L | 42 | 14 | 10 | 18 | 59 | 71 | -12 | 52 |
| 17 | SL Benfica | W W L D W | 42 | 13 | 12 | 17 | 48 | 59 | -11 | 51 |
| 18 | Athletic Club de Bilbao | L D D L W | 42 | 15 | 6 | 21 | 52 | 65 | -13 | 51 |
| 19 | Al Ittihad | L L W L L | 42 | 11 | 10 | 21 | 49 | 63 | -14 | 43 |
| 20 | Real Betis | W L L L W | 42 | 12 | 6 | 24 | 50 | 77 | -27 | 42 |
| 21 | Al Hilal | L W L D D | 42 | 8 | 16 | 18 | 51 | 73 | -22 | 40 |
| 22 | Real Sociedad | L L W D L | 42 | 9 | 13 | 20 | 48 | 75 | -27 | 40 |
